Summary:
With ocBackup Manager, it is possible to backup Sharepoint 2003, but it is important to follow these instructions to be sure and get a backup that is native and can be easily restored.

NOTE: The backup manager must be installed on the physical box where the SharePoint data and application resides.

Applies to:
OS: Windows Server 2000, Windows Server 2003, Windows Server 2008
Backup Set Type: File Backup
Backup Manager version: 5.X.X.X

Description:
1) Download the following file and place it in the c:program filesocBackup Managerbin folder. Be sure to change any parameters in the file to be specific with your companyweb and the location to where you want to place the output file. The path for the output file must already exist.

BackupSharepointScript.bat

3) In the ocBackup Manager, create a new backupset specifically for the SharePoint backup. (Its best to keep this separate)

4) Under "Backup Source", click "Advanced" and chose the path where the sharepoint backup file output is stored (same as in the backup script)

4) Under "Command Line Tool", click "Add" under the "Pre Backup" section.

5) Set the working directory to the same path as the location where you placed the BackupSharePoint2k3.bat file. (c:program filesocBackup Managerbin)

6) Set the "Command" to "BackupSharePoint2K3.bat"

7) Click "OK" and "Save Backup Settings".

See Also:
http://support.microsoft.com/kb/829112